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Monday, November 20, 2017

All About Vitamins: Vitamin B6 In reduced Risk of hypertriglyceridemia

By Kyle J. Norton.

Vitamin B6 may have a positive and profound effect in reduced risk of hypertriglyceridemia some studies suggested.

Vitamin B6, also known as pyridoxine, is a water soluble vitamin found abundantly in green peas, yams, broccoli, asparagus and turnip greens,Peanuts, sunflower seeds, cashews and hazelnuts, meat, fish etc., with functions of amino acid, carbohydrate metabolism, brain health, and liver detoxification, etc.

In the study to investigate the effect of lysine, vitamin B(6), and carnitine supplementation on both glycemia and the lipid profiles, specifically triglyceride (TG) levels of a total of 85 hypertriglyceridemic (TG> 150 mg/dL) male patients randomizedly assigned to 1 of 5 groups given supplements of lysine (1 g/d), vitamin B(6) (50 mg/d), lysine (1 g/d) + vitamin B(6) (50 mg/d), carnitine (1 g/d), or placebo for 12 weeks, after taking into account of other con founders, researchers filed the following report
1. VitaminB(6) supplementation given in an equated amount was associated with a significant reduction in total cholesterol and HDL-C of 10%.
2. Plasma total cholesterol TG was reduced by 36.6 mg/dL at 6 weeks
3. Administration of lysine and carnitine groups showed no change in lipid file

Interestingly, although chemical compound lysine and carnitine play an important role in alternating fat metabolism to induce hypertriglyceridemia, they have no impact in expression of total cholesterol and HDL-C concentrations

Further analysis, Dr. Hlais S the dead author said, "Vitamin B(6) supplementation in these male patients with hypertriglyceridemia reduced plasma total cholesterol and HDL-C concentrations". 

Other in the study to investigate the effect of elevated plasma concentrations of homocysteine, a sulfur-containing amino acid, are a risk factor for coronary, cerebral and peripheral artery disease caused by vitamin B6 and other micro nutrients deficiency suggested that the use of addition of folic acid, vitamin B12 and B6 to fibrates reduced intake of two important classes of drugs, lipid-lowering drugs and anti-hypertensive drugs, on homocysteine metabolism for prevention of CVD.

Dr. said, "(drugs) used for treatment of hypertriglyceridemia and low HDL-cholesterol, are associated with an increase of homocysteine by 20%-50%".

Taking altogether, vitamin B6 have a significant effect in reduced risk of CVD through lowering the levels of bad cholesterol and total cholesterol and reduced production of  homocysteine drugs used for treatment hypertriglyceridemia.

Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of lysine, vitamin B(6), and carnitine supplementation on the lipid profile of male patients with hypertriglyceridemia: a 12-week, open-label, randomized, placebo-controlled trial by Hlais S1, Reslan DR, Sarieddine HK, Nasreddine L, Taan G, Azar S, Obeid OA.(PubMed)
(2) Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels by Dierkes J1, Luley C, Westphal S.(PubMed)

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