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Riboflavin deficiency is asociated to increased risk factor of preeclampsia, a renowned institute study proposed.
Vitamin B2 also known as Riboflavin, is a water-soluble, yellow-orange organic compound found abundantly in milk, meat, eggs, nuts, enriched flour, green vegetables, etc. The vitamin is essential for normal cellular growth and function and best known for converting energy from protein, fat, and carbohydrates during metabolism and its antioxidant effects in oxidation-reduction reactions.
Preeclampsia is a condition of high blood pressure, sometimes accompanied with water detention in pregnant women.
According to the University Women's Hospital, in the total of 154 pregnant women with increased risk for preeclampsia observed prospectively until delivery, 33.8% among the study population are found to be riboflavin deficiency with the prevalence rate increased to the end of pregnancy.
Among these group of women, risk of developed preeclampsia is increased by 28.8% in compared to women with adequate vitamin B2. Therefore, medication and change of diet are necessary to prevent preeclampsia in induction of certain symptoms, such as gain weigh, headache, abdominal pain,...
Preeclampsia is a condition of high blood pressure, sometimes accompanied with water detention in pregnant women.
According to the University Women's Hospital, in the total of 154 pregnant women with increased risk for preeclampsia observed prospectively until delivery, 33.8% among the study population are found to be riboflavin deficiency with the prevalence rate increased to the end of pregnancy.
Among these group of women, risk of developed preeclampsia is increased by 28.8% in compared to women with adequate vitamin B2. Therefore, medication and change of diet are necessary to prevent preeclampsia in induction of certain symptoms, such as gain weigh, headache, abdominal pain,...
In vivo, reduced MTHFR activity caused by vitamin B2 deficiency is associated to increased risk of heart disease and stroke of that may influence the pregnancy outcome and mother risk.
Dr.Reilly R, the lead author in the study opinionated , "The evidence is convincing in the case which links this polymorphism with hypertension and hypertensive disorders of pregnancy, particularly preeclampsia. Furthermore, elevated blood pressure was found to be highly responsive to riboflavin intervention specifically in individuals with the MTHFR 677TT genotype.".
Taking altogether, women with history of vitamin B2 deficiency should require to test for levels of Riboflavin during the pregnancy to prevent any unfavorable delivery outcomes.
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Sources
(1) Riboflavin deficiency and preeclampsia by Wacker J1, Frühauf J, Schulz M, Chiwora FM, Volz J, Becker K.(PubMed)
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