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Tuesday, March 1, 2016

The #CurableSmoothie of Tomato, Orange and Sweet Potato for Prevention and Treatment of Hyperthyroidism in Pregnancy

Kyle J. Norton(Scholar, master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of hyperthyroidism in Pregnancy
Yield: 2 serving (about 8 ounce each)
1/2 cup tomato
1/2 cup orange
1/2 cup sweet potato
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot 1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of hyperthyroidism has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of hyperthyroidism.

Hyperthyroidism is a condition of abnormal of thyroid function in over production of thyroid hormones, affecting the modulation of oxidative stress and antioxidant defense system, in inducing the rate of neuron development in both cerebellar and cerebral cortex in offspring(1).

Beta-carotene (BC), an antioxidant with antigenotoxic properties, found in tomato, exhibited a significant antimutagenic/radioprotective activity in relation to 131I for treatment of hyoerthyroidism without inducing damage caused by the radioisotope(2).
According to the Tunceli Government Hospital, beta-carotene attenuated the expression of reactive oxygen species and impairment of the antioxidantsystem in patients with hyperthyroidism(3).
Dr. Vrca VB and colleagues at the University of Zagreb suggested, supplement therapy, after 30 and 60 days increased glutathione peroxidase and ameliorated reactive oxygen species in patients with Graves' disease(3).

Orange is a species of Citrus Sinensis, belong to the family Rutaceae and native to the Southeast Asia. Orange is round citrus fruits with finely-textured skins, orange in color and one of most popular fruits in the Dr. Parmar H and Dr. Kar A., "(beside) antiperoxidative activity, C. sinensis peel extract exhibited antithyroidal, hypoglycemic, and insulin stimulatory properties in ameliorate both hyperthyroidism and diabetes mellitus"(4) through its antioxidative/free radical-scavenging, antithyroidal and HDL-C stimulating properties(5).

Vitamin E, best known for its powerful antioxidant property is a fat soluble vitamin and can be stored in our body, found abundantly in sweet potato. In hyperthyroid rat, the vitamin induced a significant decrease in GSH-Px activity and a significant increase in GSH level, through inhibition of the burden of oxidative stress in hypehyroidism(6).
According to Dr. Dirican M. and Dr. Taş S.,vitamin E and vitamin C attenuated the level of malondialdehyde (MDA) and protected these lipoproteins from copper-induced oxidation in hyperthyroidism rat(7).
In support of the effectiveness of vitamin E for treatment of hyperthyroidism, the Università di Napoli Federico II suggested, vitamin E protected biological membranes and tissues from oxidative damage causes of elevated circulating levels of thyroid hormones(8).

The smoothie of Tomato, Orange and Sweet Potato may hold a key for further studies in production of effective natural ingredients for prevention and treatment of hyperthyroidism in pregnancy without inducing adverse effects.

Women who are at increased risk of hyperthyroidism in pregnancy, due to family history,... should drink at least one cup daily. Women with hyperthyroidism in pregnancy, should drink no more than 4 serving daily depending to the digestive toleration.



References
(1) Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II-the developmental pattern of neurons in relation to oxidative stress and antioxidant defense system by Ahmed OM1, Ahmed RG, El-Gareib AW, El-Bakry AM, Abd El-Tawab SM.(PubMed)
(2) The effect of hypothyroidism, hyperthyroidism, and their treatment on parameters of oxidative stress and antioxidant status by Erdamar H1, Demirci H, Yaman H, Erbil MK, Yakar T, Sancak B, Elbeg S, Biberoğlu G, Yetkin I.(PubMed)
(3) Oxidative Stress in Graves' Disease by Claudio Marcocci,* Marenza Leo, and Maria Antonietta Altea(PMC)
(4) Medicinal values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin, and thyroid hormones. by Parmar HS1, Kar A.(PubMed)
(5) Antiperoxidative, antithyroidal, antihyperglycemic and cardioprotective role of Citrus sinensispeel extract in male mice by Parmar HS1, Kar A.(PubMed)
(6) Antioxidant status in experimental hyperthyroidism: effect of vitamin E supplementation by Seven A1, Seymen O, Hatemi S, Hatemi H, Yiğit G, Candan G.(PubMed)
(7) Effects of vitamin E and vitamin C supplementation on plasma lipid peroxidation and on oxidation of apolipoprotein B-containing lipoproteins in experimental hyperthyroidism by Dirican M1, Taş S.(PubMed)
(8) Vitamin E management of oxidative damage-linked dysfunctions of hyperthyroid tissues by Venditti P1, Di Stefano L, Di Meo S.(PubMed)

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