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Tuesday, March 29, 2016

The #CurableSmoothie of Green Tea, Curcumin and Grape for Prevention and Treatment of Cervicitis

Kyle J. Norton(Scholar, Master of Nutrient, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Cervicitis 
Yield: 2 servings (about 8 ounces each)
1 1/2  cups grape
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of cervicitis to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.
Cervicitis is an inflammation of the cervix.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.
According to the The Catholic University of Korea, green tea extracts (polyphenon E; poly E and (-)-epigallocatechin-3-gallate [EGCG]) exhibited anti human papilloma virus (HPV) infected cervical lesions at a a 200 mg of poly E taken orally every day for eight to 12 weeks(1).
The phytochemicals of epigallocatechin gallate and polyphenols E also inhibited immortalized HPV-immortalized cervical epithelial cells and cancer cell growth. induced apoptosis through cell cycle change, according Guangxi Medical University(2).

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. Its phytochemical curcumin can stimulate prevention of multiple sexually transmitted infections of cervix caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus)(3).
According to the Air Force General Hospital of People's Liberation Army, curcumin induced apoptosis of HPV-positive human cervical cancer cells via the anti inflammatory/cellular tumor antigen NF-κB-p53-caspase-3 pathway(4).
In a phase II randomized controlled study,curcumin and curcumin containing polyherbal preparations have demonstrated anti-microbial and anti- viral properties against cervical human papillomavirus (HPV) infection(5).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape, etc. may also expressed immune modulating effects(6) against human papillomavirus (HPV)induced  inflammation(7) and malignant progression in neoplasms(8).

The effectiveness of  Green Tea, Curcumin and Grape may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  cervicitis with little or no adverse effects.

Women who are at increased risk of Cervicitis due to sexual active,.... should take 1 - 2 servings daily and women with Cervicitis should take as much as they can depending to the digestive toleration.
Life style and dietary patter change are recommended.


References
(1) Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions by Ahn WS1, Yoo J, Huh SW, Kim CK, Lee JM, Namkoong SE, Bae SM, Lee IP.(PubMed)
(2) Green tea compound in chemoprevention of cervical cancer by Zou C1, Liu H, Feugang JM, Hao Z, Chow HH, Garcia F.(PubMed)
(3) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(4) Curcumin improves the paclitaxel-induced apoptosis of HPV-positive human cervical cancer cells via the NF-κB-p53-caspase-3 pathway by Dang YP1, Yuan XY1, Tian R1, Li DG1, Liu W1.(PubMed)
(5) Clearance of cervical human papillomavirus infection by topical application of curcumin andcurcumin containing polyherbal cream: a phase II randomized controlled study by Basu P1, Dutta S, Begum R, Mittal S, Dutta PD, Bharti AC, Panda CK, Biswas J, Dey B, Talwar GP, Das BC.(PubMed)
(6) The enhancement of immune function and activation of NF-κB by resveratrol-treatment in immunosuppressive mice by Lai X1, Pei Q2, Song X1, Zhou X1, Yin Z3, Jia R4, Zou Y1, Li L1, Yue G5, Liang X1, Yin L1, Lv C1, Jing B1(PubMed)
(7) Regulation of immune responses to HPV infection and during HPV-directed immunotherapy by Bhat P1, Mattarollo SR, Gosmann C, Frazer IH, Leggatt GR.(PubMed)
(8) The role of human papilloma virus (HPV) infection in non-anogenital cancer and the promise of immunotherapy: a review by Cobos C1, Figueroa JA, Mirandola L, Colombo M, Summers G, Figueroa A, Aulakh A, Konala V, Verma R, Riaz J, Wade R, Saadeh C,Rahman RL, Pandey A, Radhi S, Nguyen DD, Jenkins M, Chiriva-Internati M, Cobos E.(PubMed)

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